https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:50541 Wed 02 Aug 2023 13:55:11 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48011 + memory T cells were the predominant sources of interleukin (IL)-4 and IL-13 transcripts whose expressions were dexamethasone resistant. Production of IL-13 by these cells was validated by IL-13-reporter mice. Neutralization of IL-13 abolished HDM/LPS-induced airway hyperresponsiveness, airway inflammation, and decreased mucus hypersecretion. Furthermore, using Ingenuity Pathway Analysis systems, we identified canonical pathways and upstream regulators that regulate the activation of basophils, ILC2, and CD8⁺ memory T cells. Our study provides mechanistic insights and an important reference resource for further understanding of the immune landscape during asthma exacerbation.]]> Thu 23 Mar 2023 10:07:13 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:11060 Sat 24 Mar 2018 08:10:37 AEDT ]]>